ea0014p336 | (1) | ECE2007
Daroszewski Jacek
, Pawlak Edyta
, Bolanowski Marek
, Slowik Miroslaw
, Frydecka Irena
Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is a B7-binding protein that plays an important role in the down-regulation of T-cell activation. CTLA-4 function is closely associated with predisposition to autoimmune diseases. A native soluble form of CTLA-4 (sCTLA-4) is reported to be present in the sera of patients suffering from autoimmune thyroid disease. In this study we report data on sCTLA-4 concentrations in patients with clinical expression of GravesÂ’ disease.<p c...